NANO-VESICLES OF SALBUTAMOL SULPHATE IN METERED DOSE INHALERS: FORMULATION, CHARACTERIZATION AND IN VITRO EVALUATION
نویسندگان
چکیده
منابع مشابه
Lung bioavailability of generic and innovator salbutamol metered dose inhalers.
BACKGROUND The aim of this study was to determine whether significant differences exist in lung bioavailability between generic (Salamol, Salbulin) and innovator (Ventolin) formulations of inhaled salbutamol given by metered dose inhalers. METHODS Ten healthy volunteers of mean age 20.5 years with a forced expiratory volume in one second (FEV1) of 112.1% predicted were studied in a randomised...
متن کاملMetered-dose inhalers and dry powder inhalers in aerosol therapy.
Inhaled drug delivery is an important part of the armamentarium of clinicians caring for patients with pulmonary disease. An increasing variety of metered-dose inhalers and dry powder inhalers are becoming available. This has been driven by the development of new formulations and the impending ban on chlorofluorocarbon propellants. The result is a proliferation of devices, resulting in a confus...
متن کاملMetered dose inhalers and spacer devices.
Easy to carry, highly effective and extremely safe, allowing accurate, consistent dose delivery, metered dose inhalers are the inhalation devices doctors and patients choose most readily the world over. Clinical response, however, may be affected by the inhalation technique used and the precise formulation in the canisters. The purpose of this review is to consider metered dose inhalers, add on...
متن کاملMetered-dose inhalers, dry powder inhalers, and transitions.
Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology. The phase-out of CFC-propelled pMDIs has stimulated the development of more efficient DPIs, but issues such as cost of device...
متن کاملFormulation and Evaluation of Transdermal Films of Salbutamol Sulphate
Transdermal drug delivery systems of salbutamol sulphate using eudragit RL100 and PVP were developed by solvent casting technique employing mercury as a substrate. Propylene glycol was used as a plasticizer. The prepared films exhibited satisfactory physico-chemical characteristics. In vitro permeation profiles across the guinea-pig dorsal skin using K-C diffusion cell are reported. Incorporati...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2017
ISSN: 0975-7058
DOI: 10.22159/ijap.2017v9i6.22448